Construct · 1 fields · 1 citations

acid-mediated invasion hypothesis: a standalone construct

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Oncology

the proposal that glycolytic tumors acidify their surroundings, killing normal cells and degrading matrix so that acid-resistant cancer cells can invade.

In oncology, acid-mediated invasion hypothesis refers to the proposal that glycolytic tumors acidify their surroundings, killing normal cells and degrading matrix so that acid-resistant cancer cells can invade. This meaning comes from Gatenby (2006) in Cancer Research.[1]

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Nearby constructs

hypothesis2 fields · 2 citationsjingle · one word, two constructs invasion3 fields · 3 citationsjingle · one word, three constructs matrix3 fields · 4 citationsjingle · one word, three constructs

References

Gatenby, R. A., Gawlinski, E. T., Gmitro, A. F., Kaylor, B., & Gillies, R. J. (2006). Acid-Mediated Tumor Invasion: a Multidisciplinary Study. Cancer Research, 66(10), 5216-5223. https://doi.org/10.1158/0008-5472.can-05-4193

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