Construct · 1 fields · 1 citations

affinity maturation: a standalone construct

One name. One construct. A landmark on the map.

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affinitymaturation1 CONSTRUCTAffinity maturation EISEN · IMMUNOLOGY

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Immunology

the rise in average antibody binding strength over the course of an immune response as higher-affinity B cell clones are selected.

In immunology, affinity maturation refers to the rise in average antibody binding strength over the course of an immune response as higher-affinity B cell clones are selected. This meaning comes from Eisen (1964) in Biochemistry.[1]

Unit
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Nearby constructs

affinity3 fields · 4 citationsjingle · one word, three constructsbinding4 fields · 4 citationsjingle · one word, four constructscell2 fields · 3 citationsjingle · one word, two constructs

References

  1. Eisen, H. N., & Siskind, G. W. (1964). Variations in Affinities of Antibodies during the Immune Response. Biochemistry, 3(7), 996-1008. https://doi.org/10.1021/bi00895a027

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