Construct · 1 fields · 1 citations

allelic exclusion: a standalone construct

One name. One construct. A landmark on the map.

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Immunology

the restriction that each lymphocyte expresses antigen receptors from only one of its two parental alleles, giving one specificity per cell.

In immunology, allelic exclusion refers to the restriction that each lymphocyte expresses antigen receptors from only one of its two parental alleles, giving one specificity per cell. This meaning comes from Pernis (1965) in The Journal of Experimental Medicine.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs exclusion4 fields · 8 citationsjingle · one word, four constructs restriction3 fields · 3 citationsjingle · one word, three constructs

References

Pernis, B., Chiappino, G., Kelus, A. S., & Gell, P. G. H. (1965). Cellular Localization of Immunoglobulins with Different Allotypic Specificities in Rabbit Lymphoid Tissues. The Journal of Experimental Medicine, 122(5), 853-876. https://doi.org/10.1084/jem.122.5.853

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