Construct · 1 fields · 1 citations

altered self hypothesis: a standalone construct

One name. One construct. A landmark on the map.

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Immunology

the idea that cytotoxic T cells recognize self MHC molecules modified by bound viral peptide rather than virus alone.

In immunology, altered self hypothesis refers to the idea that cytotoxic T cells recognize self MHC molecules modified by bound viral peptide rather than virus alone. This meaning comes from Doherty (1975) in The Lancet.[1]

Unit
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Nearby constructs

hypothesis2 fields · 2 citationsjingle · one word, two constructs virus3 fields · 5 citationsjingle · one word, three constructs

References

Doherty, P. C., & Zinkernagel, R. M. (1975). A Biological Role for the Major Histocompatibility Antigens. The Lancet, 305(7922), 1406-1409. https://doi.org/10.1016/s0140-6736(75)92610-0

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