Construct · 1 fields · 1 citations

amyloid cascade hypothesis: a standalone construct

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Cell biology

the proposal that deposition of amyloid beta protein is the initiating event that leads to the neurodegeneration of Alzheimer's disease.

In cell biology, amyloid cascade hypothesis refers to the proposal that deposition of amyloid beta protein is the initiating event that leads to the neurodegeneration of Alzheimer's disease. This meaning comes from Hardy (1992) in Science.[1]

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Nearby constructs

beta3 fields · 3 citationsjingle · one word, three constructs cascade4 fields · 4 citationsjingle · one word, four constructs cell2 fields · 3 citationsjingle · one word, two constructs

References

Hardy, J. A., & Higgins, G. A. (1992). Alzheimer's Disease: The Amyloid Cascade Hypothesis. Science, 256(5054), 184-185. https://doi.org/10.1126/science.1566067

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