Construct · 1 fields · 1 citations

astrocyte-neuron lactate shuttle: a standalone construct

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Neuroscience

the hypothesis that glutamate uptake drives astrocytes to break down glucose to lactate, which is passed to neurons as fuel.

In neuroscience, astrocyte-neuron lactate shuttle refers to the hypothesis that glutamate uptake drives astrocytes to break down glucose to lactate, which is passed to neurons as fuel. This meaning comes from Pellerin (1994) in Proceedings of the National Academy of Sciences.[1]

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Nearby constructs

break2 fields · 4 citationsjingle · one word, two constructs hypothesis2 fields · 2 citationsjingle · one word, two constructs lactate shuttle1 fields · 1 citationsanchor · a standalone construct

References

Pellerin, L., & Magistretti, P. J. (1994). Glutamate uptake into astrocytes stimulates aerobic glycolysis: a mechanism coupling neuronal activity to glucose utilization. Proceedings of the National Academy of Sciences, 91(22), 10625-10629. https://doi.org/10.1073/pnas.91.22.10625

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