Construct · 1 fields · 1 citations

Big Bang model of tumor growth: a standalone construct

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Cancer biology

the model that a tumor grows as one expansion in which most of its detectable subclones are already present early, without strong later selection.

In cancer biology, Big Bang model of tumor growth refers to the model that a tumor grows as one expansion in which most of its detectable subclones are already present early, without strong later selection. This meaning comes from Sottoriva (2015) in Nature Genetics.[1]

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Nearby constructs

cosmic microwave background1 fields · 3 citationsanchor · a standalone construct expansion4 fields · 4 citationsjingle · one word, four expansions growth4 fields · 4 citationsjingle · one word, four constructs

References

Sottoriva, A., Kang, H., Ma, Z., Graham, T. A., Salomon, M. P., Zhao, J., Marjoram, P., Siegmund, K., Press, M. F., Shibata, D., & Curtis, C. (2015). A Big Bang model of human colorectal tumor growth. Nature Genetics, 47(3), 209-216. https://doi.org/10.1038/ng.3214

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