Construct · 1 fields · 1 citations

bioisosterism: a standalone construct

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Medicinal chemistry

replacement of an atom or group with another of similar physical or chemical properties that keeps comparable biological activity.

In medicinal chemistry, bioisosterism refers to replacement of an atom or group with another of similar physical or chemical properties that keeps comparable biological activity. This meaning comes from Patani (1996) in Chemical Reviews.[1]

Unit
Recovery means
Measured by

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Nearby constructs

group4 fields · 4 citationsjingle · one word, four constructs replacement3 fields · 3 citationsjingle · one word, three constructs

References

Patani, G. A., & LaVoie, E. J. (1996). Bioisosterism: A Rational Approach in Drug Design. Chemical Reviews, 96(8), 3147-3176. https://doi.org/10.1021/cr950066q

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