Construct · 1 fields · 1 citations

cancer-associated fibroblast: a standalone construct

One name. One construct. A landmark on the map.

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Cancer biology

activated fibroblasts in the tumor stroma that remodel matrix and signal in ways that can promote or restrain cancer.

In cancer biology, cancer-associated fibroblast refers to activated fibroblasts in the tumor stroma that remodel matrix and signal in ways that can promote or restrain cancer. This meaning comes from Kalluri (2016) in Nature Reviews Cancer.[1]

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Nearby constructs

matrix3 fields · 4 citationsjingle · one word, three constructs signal5 fields · 5 citationsjingle · one word, five constructs

References

Kalluri, R. (2016). The biology and function of fibroblasts in cancer. Nature Reviews Cancer, 16(9), 582-598. https://doi.org/10.1038/nrc.2016.73

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