Construct · 1 fields · 1 citations

cancer driver mutation: a standalone construct

One name. One construct. A landmark on the map.

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Genomics

a somatic change that gives a cell a growth advantage, as distinguished from changes carried along passively.

In genomics, cancer driver mutation refers to a somatic change that gives a cell a growth advantage, as distinguished from changes carried along passively. This meaning comes from Vogelstein (2013) in Science.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs driver mutation1 fields · 1 citationsanchor · a standalone construct driver2 fields · 2 citationsjingle · one word, two constructs

References

Vogelstein, B., Papadopoulos, N., Velculescu, V. E., Zhou, S., Diaz, L. A., & Kinzler, K. W. (2013). Cancer Genome Landscapes. Science, 339(6127), 1546-1558. https://doi.org/10.1126/science.1235122

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