Construct · 1 fields · 1 citations

Cheng-Prusoff equation: a standalone construct

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Cheng-Prusoffequation1 CONSTRUCTCheng-prusoff equatiCHENG · PHARMACOLOGY

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Pharmacology

an equation converting an inhibitor's IC50 into its inhibition constant, given the substrate concentration and Km.

In pharmacology, Cheng-Prusoff equation refers to an equation converting an inhibitor's IC50 into its inhibition constant, given the substrate concentration and Km. This meaning comes from Cheng (1973) in Biochemical Pharmacology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

inhibition4 fields · 4 citationsjingle · one word, four suppressionsconcentration4 fields · 4 citationsjingle · one word, four constructsconstant2 fields · 2 citationsjingle · one word, two constructs

References

  1. Cheng, Y.-C., & Prusoff, W. H. (1973). Relationship between the inhibition constant (KI) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction. Biochemical Pharmacology, 22(23), 3099-3108. https://doi.org/10.1016/0006-2952(73)90196-2

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