Construct · 1 fields · 1 citations

chromothripsis: a standalone construct

One name. One construct. A landmark on the map.

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chromothripsis1 CONSTRUCTChromothripsisSTEPHENS · CANCER BIOLOGY

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Cancer biology

a single catastrophic event in which one or a few chromosomes shatter and are stitched back together in tumors.

In cancer biology, chromothripsis refers to a single catastrophic event in which one or a few chromosomes shatter and are stitched back together in tumors. This meaning comes from Stephens (2011) in Cell.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructschromoanagenesis1 fields · 1 citationsanchor · a standalone constructevent3 fields · 5 citationsjingle · one word, three constructs

References

  1. Stephens, P. J., Greenman, C. D., Fu, B., Yang, F., Bignell, G. R., Mudie, L. J., Pleasance, E. D., Lau, K. W., Beare, D., Stebbings, L. A., McLaren, S., Lin, M., McBride, D. J., Varela, I., Nik-Zainal, S., Leroy, C., Jia, M., Menzies, A., Butler, A. P., Teague, J. W., Quail, M. A., Burton, J., Swerdlow, H., Carter, N. P., Morsberger, L. A., Iacobuzio-Donahue, C., Follows, G. A., Green, A. R., Flanagan, A. M., Stratton, M. R., Futreal, P. A., & Campbell, P. J. (2011). Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development. Cell, 144(1), 27-40. https://doi.org/10.1016/j.cell.2010.11.055

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