Construct · 1 fields · 1 citations

clonal hematopoiesis: a standalone construct

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clonalhematopoiesis1 CONSTRUCTClonal hematopoiesisJAISWAL · GENETICS

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Genetics

the age-related expansion of blood cell clones carrying somatic mutations, which raises the risk of blood cancer and cardiovascular disease.

In genetics, clonal hematopoiesis refers to the age-related expansion of blood cell clones carrying somatic mutations, which raises the risk of blood cancer and cardiovascular disease. This meaning comes from Jaiswal (2014) in New England Journal of Medicine.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructsexpansion4 fields · 4 citationsjingle · one word, four expansionsrisk6 fields · 13 citationsjingle · one name, six constructs

References

  1. Jaiswal, S., Fontanillas, P., Flannick, J., Manning, A., Grauman, P. V., Mar, B. G., Lindsley, R. C., Mermel, C. H., Burtt, N., Chavez, A., Higgins, J. M., Moltchanov, V., Kuo, F. C., Kluk, M. J., Henderson, B., Kinnunen, L., Koistinen, H. A., Ladenvall, C., Getz, G., Correa, A., Banahan, B. F., Gabriel, S., Kathiresan, S., Stringham, H. M., McCarthy, M. I., Boehnke, M., Tuomilehto, J., Haiman, C., Groop, L., Atzmon, G., Wilson, J. G., Neuberg, D., Altshuler, D., & Ebert, B. L. (2014). Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes. New England Journal of Medicine, 371(26), 2488-2498. https://doi.org/10.1056/nejmoa1408617

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