Construct · 1 fields · 1 citations

common disease common variant hypothesis: a standalone construct

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common disease commonvariant hypothesis1 CONSTRUCTCommon disease commonREICH · GENETICS

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Genetics

the idea that the genetic risk for common diseases comes largely from common alleles of modest effect.

In genetics, common disease common variant hypothesis refers to the idea that the genetic risk for common diseases comes largely from common alleles of modest effect. This meaning comes from Reich (2001) in Trends in Genetics.[1]

Unit
Recovery means
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Nearby constructs

hypothesis2 fields · 2 citationsjingle · one word, two constructsrisk6 fields · 13 citationsjingle · one name, six constructsvariant3 fields · 5 citationsjingle · one word, three constructs

References

  1. Reich, D. E., & Lander, E. S. (2001). On the allelic spectrum of human disease. Trends in Genetics, 17(9), 502-510. https://doi.org/10.1016/s0168-9525(01)02410-6

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