Construct · 1 fields · 1 citations

common disease rare variant hypothesis: a standalone construct

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Genetics

the proposal that much inherited risk for common diseases comes from many rare variants of larger effect rather than common ones.

In genetics, common disease rare variant hypothesis refers to the proposal that much inherited risk for common diseases comes from many rare variants of larger effect rather than common ones. This meaning comes from Bodmer (2008) in Nature Genetics.[1]

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Nearby constructs

hypothesis2 fields · 2 citationsjingle · one word, two constructs risk6 fields · 13 citationsjingle · one name, six constructs variant3 fields · 5 citationsjingle · one word, three constructs

References

Bodmer, W., & Bonilla, C. (2008). Common and rare variants in multifactorial susceptibility to common diseases. Nature Genetics, 40(6), 695-701. https://doi.org/10.1038/ng.f.136

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