Construct · 1 fields · 1 citations

conformational masking: a standalone construct

One name. One construct. A landmark on the map.

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conformationalmasking1 CONSTRUCTConformational maskingKWONG · IMMUNOLOGY

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Immunology

an evasion strategy in which a pathogen hides a conserved vulnerable site behind flexible surface structures until it engages its receptor.

In immunology, conformational masking refers to an evasion strategy in which a pathogen hides a conserved vulnerable site behind flexible surface structures until it engages its receptor. This meaning comes from Kwong (2002) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

receptor2 fields · 2 citationsjingle · one word, two constructsstrategy4 fields · 4 citationsjingle · one word, four constructssurface3 fields · 3 citationsjingle · one word, three constructs

References

  1. Kwong, P. D., Doyle, M. L., Casper, D. J., Cicala, C., Leavitt, S. A., Majeed, S., Steenbeke, T. D., Venturi, M., Chaiken, I., Fung, M., Katinger, H., Parren, P. W. I. H., Robinson, J., Van Ryk, D., Wang, L., Burton, D. R., Freire, E., Wyatt, R., Sodroski, J., Hendrickson, W. A., & Arthos, J. (2002). HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites. Nature, 420(6916), 678-682. https://doi.org/10.1038/nature01188

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