Construct · 1 fields · 1 citations

Craig plot: a standalone construct

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Medicinal chemistry

plot of substituents by Hammett electronic constant against hydrophobic constant, used to pick substituent sets that vary the two independently.

In medicinal chemistry, Craig plot refers to plot of substituents by Hammett electronic constant against hydrophobic constant, used to pick substituent sets that vary the two independently. This meaning comes from Craig (1971) in Journal of Medicinal Chemistry.[1]

Unit
Recovery means
Measured by

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constant2 fields · 2 citationsjingle · one word, two constructs plot1 fields · 3 citationsanchor · a standalone construct

References

Craig, P. N. (1971). Interdependence between physical parameters and selection of substituent groups for correlation studies. Journal of Medicinal Chemistry, 14(8), 680-684. https://doi.org/10.1021/jm00290a004

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