Construct · 1 fields · 1 citations

cryptic determinant: a standalone construct

One name. One construct. A landmark on the map.

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Immunology

a self or foreign epitope poorly displayed during normal processing, so T cells against it escape tolerance and can drive autoimmunity.

In immunology, cryptic determinant refers to a self or foreign epitope poorly displayed during normal processing, so T cells against it escape tolerance and can drive autoimmunity. This meaning comes from Sercarz (1993) in Annual Review of Immunology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

determinant3 fields · 5 citationsjingle · one word, three constructs drive2 fields · 2 citationsjingle · one word, two constructs escape2 fields · 2 citationsjingle · one word, two constructs

References

Sercarz, E. E., Lehmann, P. V., Ametani, A., Benichou, G., Miller, A., & Moudgil, K. (1993). Dominance and Crypticity of T Cell Antigenic Determinants. Annual Review of Immunology, 11(1), 729-766. https://doi.org/10.1146/annurev.iy.11.040193.003501

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