Construct · 1 fields · 1 citations

cuproptosis: a standalone construct

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Cell biology

a copper-dependent form of regulated cell death caused by copper binding to lipoylated enzymes of the TCA cycle.

In cell biology, cuproptosis refers to a copper-dependent form of regulated cell death caused by copper binding to lipoylated enzymes of the TCA cycle. This meaning comes from Tsvetkov (2022) in Science.[1]

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs cell2 fields · 3 citationsjingle · one word, two constructs cycle4 fields · 4 citationsjingle · one word, four constructs

References

Tsvetkov, P., Coy, S., Petrova, B., Dreishpoon, M., Verma, A., Abdusamad, M., Rossen, J., Joesch-Cohen, L., Humeidi, R., Spangler, R. D., Eaton, J. K., Frenkel, E., Kocak, M., Corsello, S. M., Lutsenko, S., Kanarek, N., Santagata, S., & Golub, T. R. (2022). Copper induces cell death by targeting lipoylated TCA cycle proteins. Science, 375(6586), 1254-1261. https://doi.org/10.1126/science.abf0529

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