Construct · 1 fields · 1 citations

CUT&RUN: a standalone construct

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Biotechnology

method mapping protein-DNA binding by tethering a nuclease to an antibody and releasing only the cut fragments.

In biotechnology, CUT&RUN refers to method mapping protein-DNA binding by tethering a nuclease to an antibody and releasing only the cut fragments. This meaning comes from Skene (2017) in eLife.[1]

Unit
Recovery means
Measured by

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Nearby constructs

CUT and RUN1 fields · 1 citationsanchor · a standalone construct binding4 fields · 4 citationsjingle · one word, four constructs caesura1 fields · 1 citationsanchor · a standalone construct

References

Skene, P. J., & Henikoff, S. (2017). An efficient targeted nuclease strategy for high-resolution mapping of DNA binding sites. eLife, 6. https://doi.org/10.7554/elife.21856

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