Construct · 1 fields · 1 citations

deep mutational scanning: a standalone construct

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Protein engineering

measuring the functional effect of nearly every single-residue variant of a protein in one selection experiment.

In protein engineering, deep mutational scanning refers to measuring the functional effect of nearly every single-residue variant of a protein in one selection experiment. This meaning comes from Fowler (2014) in Nature Methods.[1]

Unit
Recovery means
Measured by

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Nearby constructs

selection4 fields · 5 citationsjingle · one word, four constructs variant3 fields · 5 citationsjingle · one word, three constructs

References

Fowler, D. M., & Fields, S. (2014). Deep mutational scanning: a new style of protein science. Nature Methods, 11(8), 801-807. https://doi.org/10.1038/nmeth.3027

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