Construct · 1 fields · 1 citations

disease-associated microglia: a standalone construct

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Neuroimmunology

a microglial state, defined by a distinct gene expression program, that appears around amyloid plaques and is proposed to limit neurodegeneration.

In neuroimmunology, disease-associated microglia refers to a microglial state, defined by a distinct gene expression program, that appears around amyloid plaques and is proposed to limit neurodegeneration. This meaning comes from Keren-Shaul (2017) in Cell.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs expression4 fields · 4 citationsjingle · one word, four constructs limit3 fields · 3 citationsjingle · one word, three constructs

References

Keren-Shaul, H., Spinrad, A., Weiner, A., Matcovitch-Natan, O., Dvir-Szternfeld, R., Ulland, T. K., David, E., Baruch, K., Lara-Astaiso, D., Toth, B., Itzkovitz, S., Colonna, M., Schwartz, M., & Amit, I. (2017). A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease. Cell, 169(7), 1276-1290.e17. https://doi.org/10.1016/j.cell.2017.05.018

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