Construct · 1 fields · 1 citations

drug rebinding: a standalone construct

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Pharmacology

repeated binding of a dissociated drug molecule to the same or nearby targets before it diffuses away, prolonging drug action beyond simple dissociation kinetics.

In pharmacology, drug rebinding refers to repeated binding of a dissociated drug molecule to the same or nearby targets before it diffuses away, prolonging drug action beyond simple dissociation kinetics. This meaning comes from Vauquelin (2010) in British Journal of Pharmacology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

action3 fields · 6 citationsjingle · one word, three constructs binding4 fields · 4 citationsjingle · one word, four constructs dissociation3 fields · 3 citationsjingle · one word, three constructs

References

Vauquelin, G., & Charlton, S. J. (2010). Long‐lasting target binding and rebinding as mechanisms to prolongin vivodrug action. British Journal of Pharmacology, 161(3), 488-508. https://doi.org/10.1111/j.1476-5381.2010.00936.x

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