Construct · 1 fields · 1 citations

dual SMAD inhibition: a standalone construct

One name. One construct. A landmark on the map.

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Stem cell biology

driving human pluripotent stem cells to neural cells efficiently by blocking two SMAD signalling pathways at once.

In stem cell biology, dual SMAD inhibition refers to driving human pluripotent stem cells to neural cells efficiently by blocking two SMAD signalling pathways at once. This meaning comes from Chambers (2009) in Nature Biotechnology.[1]

Unit
Recovery means
Measured by

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs inhibition4 fields · 4 citationsjingle · one word, four suppressions stem2 fields · 2 citationsjingle · one word, two constructs

References

Chambers, S. M., Fasano, C. A., Papapetrou, E. P., Tomishima, M., Sadelain, M., & Studer, L. (2009). Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling. Nature Biotechnology, 27(3), 275-280. https://doi.org/10.1038/nbt.1529

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