Construct · 1 fields · 1 citations

electrostatic preorganization: a standalone construct

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Enzymology

the theory that enzyme active sites are built with dipoles already oriented to stabilize the transition state, so less reorganization energy is paid than in water.

In enzymology, electrostatic preorganization refers to the theory that enzyme active sites are built with dipoles already oriented to stabilize the transition state, so less reorganization energy is paid than in water. This meaning comes from Warshel (1998) in Journal of Biological Chemistry.[1]

Unit
Recovery means
Measured by

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Nearby constructs

energy5 fields · 10 citationsjingle · one word, five constructs preorganization1 fields · 1 citationsanchor · a standalone construct state4 fields · 6 citationsjingle · one word, four constructs

References

Warshel, A. (1998). Electrostatic Origin of the Catalytic Power of Enzymes and the Role of Preorganized Active Sites. Journal of Biological Chemistry, 273(42), 27035-27038. https://doi.org/10.1074/jbc.273.42.27035

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