Construct · 1 fields · 1 citations

epitope spreading: a standalone construct

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Immunology

the broadening of an immune response over time from the first targeted epitope to other, previously ignored epitopes on the same or related antigens.

In immunology, epitope spreading refers to the broadening of an immune response over time from the first targeted epitope to other, previously ignored epitopes on the same or related antigens. This meaning comes from Lehmann (1992) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

response4 fields · 4 citationsjingle · one word, four constructs

References

Lehmann, P. V., Forsthuber, T., Miller, A., & Sercarz, E. E. (1992). Spreading of T-cell autoimmunity to cryptic determinants of an autoantigen. Nature, 358(6382), 155-157. https://doi.org/10.1038/358155a0

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