Construct · 1 fields · 1 citations

escape from flatland: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
escape fromflatland1 CONSTRUCTEscape from flatlandLOVERING · MEDICINAL CHEMISTRY

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Medicinal chemistry

proposal that compounds with more sp3-hybridized carbons and stereocenters are more likely to progress clinically than flat aromatic molecules.

In medicinal chemistry, escape from flatland refers to proposal that compounds with more sp3-hybridized carbons and stereocenters are more likely to progress clinically than flat aromatic molecules. This meaning comes from Lovering (2009) in Journal of Medicinal Chemistry.[1]

Unit
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Nearby constructs

escape2 fields · 2 citationsjingle · one word, two constructs

References

  1. Lovering, F., Bikker, J., & Humblet, C. (2009). Escape from Flatland: Increasing Saturation as an Approach to Improving Clinical Success. Journal of Medicinal Chemistry, 52(21), 6752-6756. https://doi.org/10.1021/jm901241e

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