Construct · 1 fields · 1 citations

excitation-inhibition imbalance hypothesis of autism: a standalone construct

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Neuroscience

the proposal that autism arises from an increased ratio of excitation to inhibition in key neural circuits, making them noisy and hyperexcitable.

In neuroscience, excitation-inhibition imbalance hypothesis of autism refers to the proposal that autism arises from an increased ratio of excitation to inhibition in key neural circuits, making them noisy and hyperexcitable. This meaning comes from Rubenstein (2003) in Genes, Brain and Behavior.[1]

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Nearby constructs

excitation3 fields · 3 citationsjingle · one word, three constructs hypothesis2 fields · 2 citationsjingle · one word, two constructs inhibition4 fields · 4 citationsjingle · one word, four suppressions

References

Rubenstein, J. L. R., & Merzenich, M. M. (2003). Model of autism: increased ratio of excitation/inhibition in key neural systems. Genes, Brain and Behavior, 2(5), 255-267. https://doi.org/10.1034/j.1601-183x.2003.00037.x

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