Construct · 1 fields · 1 citations

Free-Wilson analysis: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
Free-Wilsonanalysis1 CONSTRUCTFree-Wilson analysisFREE · MEDICINAL CHEMISTRY

A single standalone construct; nearby constructs are located against it in the Collider. Tap a field for its definition, unit, and measures.

Medicinal chemistry

additive model that assigns each substituent at each position a fixed contribution to biological activity, estimated from a congeneric series.

In medicinal chemistry, Free-Wilson analysis refers to additive model that assigns each substituent at each position a fixed contribution to biological activity, estimated from a congeneric series. This meaning comes from Free (1964) in Journal of Medicinal Chemistry.[1]

Unit
Recovery means
Measured by

Next

Run it through the Collider, or take the citations with you.

See how Free-Wilson analysis sits against neighbouring constructs in the Collider, or export every reference on this page in one click.

Open in ColliderExport BibTeXReport this entry

Nearby constructs

contribution2 fields · 3 citationsjingle · one word, two carriersgeneralized additive model1 fields · 1 citationsanchor · a standalone constructmodel3 fields · 3 citationsjingle · one word, three constructs

References

  1. Free, S. M., & Wilson, J. W. (1964). A Mathematical Contribution to Structure-Activity Studies. Journal of Medicinal Chemistry, 7(4), 395-399. https://doi.org/10.1021/jm00334a001

Cited on this page?

Confirm your construct, or correct us.

If your work is cited behind one of these entries, you know better than we do whether we captured the meaning right. Confirm it, suggest an edit, or dispute it, and your name goes on the entry as an author who has checked it, linked to your ORCID.

Claim your construct