Construct · 1 fields · 1 citations

functional selectivity: a standalone construct

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Pharmacology

the ability of different ligands acting at one receptor to favor different downstream signaling pathways.

In pharmacology, functional selectivity refers to the ability of different ligands acting at one receptor to favor different downstream signaling pathways. This meaning comes from Urban (2007) in The Journal of Pharmacology and Experimental Therapeutics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

receptor2 fields · 2 citationsjingle · one word, two constructs selectivity4 fields · 5 citationsjingle · one word, four constructs

References

Urban, J. D., Clarke, W. P., von Zastrow, M., Nichols, D. E., Kobilka, B., Weinstein, H., Javitch, J. A., Roth, B. L., Christopoulos, A., Sexton, P. M., Miller, K. J., Spedding, M., & Mailman, R. B. (2007). Functional Selectivity and Classical Concepts of Quantitative Pharmacology. The Journal of Pharmacology and Experimental Therapeutics, 320(1), 1-13. https://doi.org/10.1124/jpet.106.104463

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