Construct · 1 fields · 1 citations

gain-of-function research: a standalone construct

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gain-of-functionresearch1 CONSTRUCTGain-of-functionCASADEVALL · RESEARCH ETHICS

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Research ethics

experiments that give pathogens new or enhanced properties such as transmissibility, raising questions of benefit and biosafety.

In research ethics, gain-of-function research refers to experiments that give pathogens new or enhanced properties such as transmissibility, raising questions of benefit and biosafety. This meaning comes from Casadevall (2014) in mBio.[1]

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References

  1. Casadevall, A., & Imperiale, M. J. (2014). Risks and Benefits of Gain-of-Function Experiments with Pathogens of Pandemic Potential, Such as Influenza Virus: a Call for a Science-Based Discussion. mBio, 5(4). https://doi.org/10.1128/mbio.01730-14

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