Construct · 1 fields · 1 citations

genetic colocalization: a standalone construct

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Genetics and genomics

a test of whether two association signals, such as a disease locus and an expression locus, share the same causal variant.

In genetics and genomics, genetic colocalization refers to a test of whether two association signals, such as a disease locus and an expression locus, share the same causal variant. This meaning comes from Giambartolomei (2014) in PLoS Genetics.[1]

Unit
Recovery means
Measured by

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Nearby constructs

association4 fields · 4 citationsjingle · one word, four constructs expression4 fields · 4 citationsjingle · one word, four constructs locus3 fields · 8 citationsjingle · one word, three constructs

References

Giambartolomei, C., Vukcevic, D., Schadt, E. E., Franke, L., Hingorani, A. D., Wallace, C., & Plagnol, V. (2014). Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics. PLoS Genetics, 10(5), e1004383. https://doi.org/10.1371/journal.pgen.1004383

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