Construct · 1 fields · 1 citations

genetic toggle switch: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

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Systems biology

a synthetic circuit of two mutually repressing genes that settles into one of two stable states and can be flipped by a signal.

In systems biology, genetic toggle switch refers to a synthetic circuit of two mutually repressing genes that settles into one of two stable states and can be flipped by a signal. This meaning comes from Gardner (2000) in Nature.[1]

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Nearby constructs

switch2 fields · 4 citationsjingle · one word, two constructs bistability1 fields · 1 citationsanchor · a standalone construct circuit1 fields · 1 citationsanchor · a standalone construct

References

Gardner, T. S., Cantor, C. R., & Collins, J. J. (2000). Construction of a genetic toggle switch in Escherichia coli. Nature, 403(6767), 339-342. https://doi.org/10.1038/35002131

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