Construct · 1 fields · 1 citations

Gilbert syndrome: a standalone construct

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Pharmacogenomics

a common inherited mild rise in unconjugated bilirubin due to reduced UGT1A1 expression, also linked to altered metabolism of some drugs.

In pharmacogenomics, Gilbert syndrome refers to a common inherited mild rise in unconjugated bilirubin due to reduced UGT1A1 expression, also linked to altered metabolism of some drugs. This meaning comes from Bosma (1995) in New England Journal of Medicine.[1]

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Nearby constructs

expression4 fields · 4 citationsjingle · one word, four constructs metabolism3 fields · 3 citationsjingle · one word, three constructs pharmacogenomics1 fields · 1 citationsanchor · a standalone construct

References

Bosma, P. J., Chowdhury, J. R., Bakker, C., Gantla, S., de Boer, A., Oostra, B. A., Lindhout, D., Tytgat, G. N. J., Jansen, P. L. M., Elferink, R. P. J. O., & Chowdhury, N. R. (1995). The Genetic Basis of the Reduced Expression of Bilirubin UDP-Glucuronosyltransferase 1 in Gilbert's Syndrome. New England Journal of Medicine, 333(18), 1171-1175. https://doi.org/10.1056/nejm199511023331802

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