Construct · 1 fields · 1 citations

Gini coefficient of kinase selectivity: a standalone construct

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Medicinal chemistry

adaptation of the Gini inequality index to inhibition profiles across a kinase panel, where values near one mean inhibition concentrated on few kinases.

In medicinal chemistry, Gini coefficient of kinase selectivity refers to adaptation of the Gini inequality index to inhibition profiles across a kinase panel, where values near one mean inhibition concentrated on few kinases. This meaning comes from Graczyk (2007) in Journal of Medicinal Chemistry.[1]

Unit
Recovery means
Measured by

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Nearby constructs

adaptation5 fields · 7 citationsjingle · one word, five constructs Gini coefficient1 fields · 3 citationsanchor · a standalone construct index5 fields · 11 citationsjingle · one word, five constructs

References

Graczyk, P. P. (2007). Gini Coefficient: A New Way To Express Selectivity of Kinase Inhibitors against a Family of Kinases. Journal of Medicinal Chemistry, 50(23), 5773-5779. https://doi.org/10.1021/jm070562u

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