Construct · 1 fields · 1 citations

glucocorticoid cascade hypothesis: a standalone construct

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Endocrinology

the proposal that prolonged glucocorticoid exposure damages the hippocampus, which then weakens feedback and raises glucocorticoids further.

In endocrinology, glucocorticoid cascade hypothesis refers to the proposal that prolonged glucocorticoid exposure damages the hippocampus, which then weakens feedback and raises glucocorticoids further. This meaning comes from Sapolsky (1986) in Endocrine Reviews.[1]

Unit
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Nearby constructs

cascade4 fields · 4 citationsjingle · one word, four constructs exposure6 fields · 13 citationsjingle · one name, six constructs feedback4 fields · 5 citationsjingle · one word, four constructs

References

Sapolsky, R. M., Krey, L. C., & McEWEN, B. S. (1986). The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis. Endocrine Reviews, 7(3), 284-301. https://doi.org/10.1210/edrv-7-3-284

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