Construct · 1 fields · 1 citations

Hansch-Fujita pi constant: a standalone construct

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Medicinal chemistry

substituent constant equal to the change in log partition coefficient caused by a substituent, used as a hydrophobic term in structure-activity equations.

In medicinal chemistry, Hansch-Fujita pi constant refers to substituent constant equal to the change in log partition coefficient caused by a substituent, used as a hydrophobic term in structure-activity equations. This meaning comes from Fujita (1964) in Journal of the American Chemical Society.[1]

Unit
Recovery means
Measured by

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Nearby constructs

constant2 fields · 2 citationsjingle · one word, two constructs octanol-water partition coefficient1 fields · 1 citationsanchor · a standalone construct partition3 fields · 3 citationsjingle · one word, three constructs

References

Fujita, T., Iwasa, J., & Hansch, C. (1964). A New Substituent Constant, π, Derived from Partition Coefficients. Journal of the American Chemical Society, 86(23), 5175-5180. https://doi.org/10.1021/ja01077a028

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