Construct · 1 fields · 1 citations

hippocampal dysregulation model of psychosis: a standalone construct

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hippocampal dysregulationmodel of psychosis1 CONSTRUCTHippocampalLODGE · BIOLOGICAL PSYCHIATRY

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Biological psychiatry

model in which hippocampal overactivity drives excess dopamine neuron firing in the midbrain, producing the dopamine dysregulation linked to psychosis.

In biological psychiatry, hippocampal dysregulation model of psychosis refers to model in which hippocampal overactivity drives excess dopamine neuron firing in the midbrain, producing the dopamine dysregulation linked to psychosis. This meaning comes from Lodge (2011) in Trends in Pharmacological Sciences.[1]

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firing2 fields · 2 citationsjingle · one word, two constructsmodel3 fields · 3 citationsjingle · one word, three constructs

References

  1. Lodge, D. J., & Grace, A. A. (2011). Hippocampal dysregulation of dopamine system function and the pathophysiology of schizophrenia. Trends in Pharmacological Sciences, 32(9), 507-513. https://doi.org/10.1016/j.tips.2011.05.001

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