Construct · 1 fields · 1 citations

HLA-associated drug hypersensitivity: a standalone construct

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Pharmacogenomics

an immune-mediated adverse drug reaction whose risk is strongly tied to carrying a particular HLA allele.

In pharmacogenomics, HLA-associated drug hypersensitivity refers to an immune-mediated adverse drug reaction whose risk is strongly tied to carrying a particular HLA allele. This meaning comes from Mallal (2002) in The Lancet.[1]

Unit
Recovery means
Measured by

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Nearby constructs

adverse drug reaction1 fields · 1 citationsanchor · a standalone construct allele3 fields · 5 citationsjingle · one word, three constructs pharmacogenomics1 fields · 1 citationsanchor · a standalone construct

References

Mallal, S., Nolan, D., Witt, C., Masel, G., Martin, A., Moore, C., Sayer, D., Castley, A., Mamotte, C., Maxwell, D., James, I., & Christiansen, F. (2002). Association between presence of HLA-B*5701, HLA-DR7, and HLA-DQ3 and hypersensitivity to HIV-1 reverse-transcriptase inhibitor abacavir. The Lancet, 359(9308), 727-732. https://doi.org/10.1016/s0140-6736(02)07873-x

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