Construct · 1 fields · 1 citations

immune checkpoint blockade: a standalone construct

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Immunology

relief of inhibitory receptor signalling on T cells so that an existing antitumour response can proceed.

In immunology, immune checkpoint blockade refers to relief of inhibitory receptor signalling on T cells so that an existing antitumour response can proceed. This meaning comes from Leach (1996) in Science.[1]

Unit
Recovery means
Measured by

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Nearby constructs

blockade1 fields · 2 citationsanchor · a standalone construct checkpoint3 fields · 3 citationsjingle · one word, three constructs receptor2 fields · 2 citationsjingle · one word, two constructs

References

Leach, D. R., Krummel, M. F., & Allison, J. P. (1996). Enhancement of Antitumor Immunity by CTLA-4 Blockade. Science, 271(5256), 1734-1736. https://doi.org/10.1126/science.271.5256.1734

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