Construct · 1 fields · 1 citations

immunological ignorance: a standalone construct

One name. One construct. A landmark on the map.

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immunologicalignorance1 CONSTRUCTImmunological ignoranceOHASHI · IMMUNOLOGY

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Immunology

a state in which self-reactive lymphocytes persist and stay functional but do not respond because they never meet their antigen in an activating context.

In immunology, immunological ignorance refers to a state in which self-reactive lymphocytes persist and stay functional but do not respond because they never meet their antigen in an activating context. This meaning comes from Ohashi (1991) in Cell.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructscontext4 fields · 7 citationsjingle · one word, four constructsstate4 fields · 6 citationsjingle · one word, four constructs

References

  1. Ohashi, P. S., Oehen, S., Buerki, K., Pircher, H., Ohashi, C. T., Odermatt, B., Malissen, B., Zinkernagel, R. M., & Hengartner, H. (1991). Ablation of “tolerance” and induction of diabetes by virus infection in viral antigen transgenic mice. Cell, 65(2), 305-317. https://doi.org/10.1016/0092-8674(91)90164-t

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