Construct · 1 fields · 1 citations

in vitro to in vivo extrapolation: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed
in vitro to invivo extrapolation1 CONSTRUCTIn vitro to in vivoWETMORE · TOXICOKINETICS

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Toxicokinetics

converting active concentrations from cell-based assays into equivalent human doses using toxicokinetic data, to compare with exposure.

In toxicokinetics, in vitro to in vivo extrapolation refers to converting active concentrations from cell-based assays into equivalent human doses using toxicokinetic data, to compare with exposure. This meaning comes from Wetmore (2011) in Toxicological Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

exposure6 fields · 13 citationsjingle · one name, six constructstoxicokinetics1 fields · 1 citationsanchor · a standalone construct

References

  1. Wetmore, B. A., Wambaugh, J. F., Ferguson, S. S., Sochaski, M. A., Rotroff, D. M., Freeman, K., Clewell, H. J., Dix, D. J., Andersen, M. E., Houck, K. A., Allen, B., Judson, R. S., Singh, R., Kavlock, R. J., Richard, A. M., & Thomas, R. S. (2011). Integration of Dosimetry, Exposure, and High-Throughput Screening Data in Chemical Toxicity Assessment. Toxicological Sciences, 125(1), 157-174. https://doi.org/10.1093/toxsci/kfr254

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