Construct · 1 fields · 1 citations

indirect response model: a standalone construct

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indirectresponse model1 CONSTRUCTIndirect response modelDAYNEKA · PHARMACOMETRICS

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Pharmacometrics

family of four pharmacodynamic models in which a drug stimulates or inhibits the production or loss of a response variable rather than acting on it directly.

In pharmacometrics, indirect response model refers to family of four pharmacodynamic models in which a drug stimulates or inhibits the production or loss of a response variable rather than acting on it directly. This meaning comes from Dayneka (1993) in Journal of Pharmacokinetics and Biopharmaceutics.[1]

Unit
Recovery means
Measured by

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References

  1. Dayneka, N. L., Garg, V., & Jusko, W. J. (1993). Comparison of four basic models of indirect pharmacodynamic responses. Journal of Pharmacokinetics and Biopharmaceutics, 21(4), 457-478. https://doi.org/10.1007/bf01061691

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