Construct · 1 fields · 1 citations

local frustration: a standalone construct

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Biophysics

sites in a native protein where interactions are energetically unfavorable relative to alternatives, often clustered at binding and functional regions.

In biophysics, local frustration refers to sites in a native protein where interactions are energetically unfavorable relative to alternatives, often clustered at binding and functional regions. This meaning comes from Ferreiro (2007) in Proceedings of the National Academy of Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

binding4 fields · 4 citationsjingle · one word, four constructs frustration3 fields · 7 citationsjingle · one word, three constructs

References

Ferreiro, D. U., Hegler, J. A., Komives, E. A., & Wolynes, P. G. (2007). Localizing frustration in native proteins and protein assemblies. Proceedings of the National Academy of Sciences, 104(50), 19819-19824. https://doi.org/10.1073/pnas.0709915104

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