Construct · 1 fields · 1 citations

Lynch syndrome: a standalone construct

One name. One construct. A landmark on the map.

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Lynchsyndrome1 CONSTRUCTLynch syndromeLYNCH · MEDICAL GENETICS

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Medical genetics

an autosomal dominant cancer predisposition from germline mismatch-repair gene variants, conferring high risks of colorectal, endometrial and other cancers.

In medical genetics, Lynch syndrome refers to an autosomal dominant cancer predisposition from germline mismatch-repair gene variants, conferring high risks of colorectal, endometrial and other cancers. This meaning comes from Lynch (2003) in New England Journal of Medicine.[1]

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Nearby constructs

dominant1 fields · 1 citationsanchor · a standalone constructPREMM51 fields · 1 citationsanchor · a standalone constructrevised Bethesda guidelines1 fields · 1 citationsanchor · a standalone construct

References

  1. Lynch, H. T., & de la Chapelle, A. (2003). Hereditary Colorectal Cancer. New England Journal of Medicine, 348(10), 919-932. https://doi.org/10.1056/nejmra012242

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