Construct · 1 fields · 1 citations

microsatellite instability: a standalone construct

One name. One construct. A landmark on the map.

● anchor · a standalone construct Nearest construct by meaning·not indexed

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Cancer biology

widespread changes in the length of short repeated DNA sequences in tumors, caused by faulty mismatch repair.

In cancer biology, microsatellite instability refers to widespread changes in the length of short repeated DNA sequences in tumors, caused by faulty mismatch repair. This meaning comes from Ionov (1993) in Nature.[1]

Unit
Recovery means
Measured by

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Nearby constructs

instability3 fields · 3 citationsjingle · one word, three constructs mismatch repair1 fields · 1 citationsanchor · a standalone construct revised Bethesda guidelines1 fields · 1 citationsanchor · a standalone construct

References

Ionov, Y., Peinado, M. A., Malkhosyan, S., Shibata, D., & Perucho, M. (1993). Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis. Nature, 363(6429), 558-561. https://doi.org/10.1038/363558a0

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