Construct · 1 fields · 1 citations

necroptosis: a standalone construct

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Cell biology

a regulated, caspase-independent form of necrotic cell death that can be blocked by necrostatin-type inhibitors.

In cell biology, necroptosis refers to a regulated, caspase-independent form of necrotic cell death that can be blocked by necrostatin-type inhibitors. This meaning comes from Degterev (2005) in Nature Chemical Biology.[1]

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Nearby constructs

cell2 fields · 3 citationsjingle · one word, two constructs form4 fields · 7 citationsjingle · one word, four constructs

References

Degterev, A., Huang, Z., Boyce, M., Li, Y., Jagtap, P., Mizushima, N., Cuny, G. D., Mitchison, T. J., Moskowitz, M. A., & Yuan, J. (2005). Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury. Nature Chemical Biology, 1(2), 112-119. https://doi.org/10.1038/nchembio711

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