Construct · 1 fields · 1 citations

negative cooperativity: a standalone construct

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Biochemistry

binding behavior in which ligand binding at one site lowers affinity at other sites, flattening the binding curve below a hyperbola.

In biochemistry, negative cooperativity refers to binding behavior in which ligand binding at one site lowers affinity at other sites, flattening the binding curve below a hyperbola. This meaning comes from Levitzki (1969) in Proceedings of the National Academy of Sciences.[1]

Unit
Recovery means
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Nearby constructs

affinity3 fields · 4 citationsjingle · one word, three constructs binding4 fields · 4 citationsjingle · one word, four constructs cooperativity3 fields · 3 citationsinvariant · one construct, three systems

References

Levitzki, A., & Koshland, D. E. (1969). Negative Cooperativity in Regulatory Enzymes. Proceedings of the National Academy of Sciences, 62(4), 1121-1128. https://doi.org/10.1073/pnas.62.4.1121

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