Construct · 1 fields · 1 citations

nonsense-mediated decay: a standalone construct

One name. One construct. A landmark on the map.

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Molecular biology

surveillance pathway that degrades transcripts carrying a premature termination codon, lowering the amount of truncated protein made.

In molecular biology, nonsense-mediated decay refers to surveillance pathway that degrades transcripts carrying a premature termination codon, lowering the amount of truncated protein made. This meaning comes from Losson (1979) in Proceedings of the National Academy of Sciences.[1]

Unit
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Nearby constructs

decay4 fields · 5 citationsjingle · one word, four constructs premature termination1 fields · 1 citationsanchor · a standalone construct surveillance3 fields · 3 citationsjingle · one word, three constructs

References

Losson, R., & Lacroute, F. (1979). Interference of nonsense mutations with eukaryotic messenger RNA stability. Proceedings of the National Academy of Sciences, 76(10), 5134-5137. https://doi.org/10.1073/pnas.76.10.5134

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