Construct · 1 fields · 1 citations

nucleation-condensation mechanism: a standalone construct

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nucleation-condensationmechanism1 CONSTRUCTNucleation-condensationFERSHT · BIOPHYSICS

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Biophysics

a folding mechanism in which a weakly formed local nucleus and long-range tertiary contacts consolidate together in a single cooperative transition state.

In biophysics, nucleation-condensation mechanism refers to a folding mechanism in which a weakly formed local nucleus and long-range tertiary contacts consolidate together in a single cooperative transition state. This meaning comes from Fersht (1995) in Proceedings of the National Academy of Sciences.[1]

Unit
Recovery means
Measured by

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Nearby constructs

mechanism4 fields · 4 citationsjingle · one word, four constructsnucleus4 fields · 5 citationsjingle · one word, four constructsstate4 fields · 6 citationsjingle · one word, four constructs

References

  1. Fersht, A. R. (1995). Optimization of rates of protein folding: the nucleation-condensation mechanism and its implications. Proceedings of the National Academy of Sciences, 92(24), 10869-10873. https://doi.org/10.1073/pnas.92.24.10869

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